In vitro and in vivo ocular biocompatibility of electrospun poly(ɛ-caprolactone) nanofibers
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چکیده
منابع مشابه
Preparation and characterization of CS/ PEO/ cefazolin nanofibers with in vitro and in vivo testing
Objective(S): Electrospinning of chitosan/polyethylene oxide (CS/PEO) nanofibers with the addition of cefazolin to create nanofibers with antimicrobial properties were examined. Methods: Polymeric nanofibers including CS/PEO and CS/PEO /cefazolin, were produced by electrospinning method. The range of nanofiber was 60-100 nm in diameter and measured with I...
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Dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. The aim of this study is to develop ocular dorzolamide HCl nanoliposomes (DRZ – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. Nanoliposomes were prepared using Reverse-phase evaporation vesicle (REV) and thin layer hydration (TLH...
متن کاملOcular Dorzolamide Nanoliposomes for Prolonged IOP Reduction: in-vitro and in-vivo Evaluation in Rabbits
Dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. The aim of this study is to develop ocular dorzolamide HCl nanoliposomes (DRZ – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. Nanoliposomes were prepared using Reverse-phase evaporation vesicle (REV) and thin layer hydration (TLH...
متن کاملElectrospun Nanofibers and their Application in Tissue Repair and Engineering
Introduction: Tissue engineering is the repair and replacement of damaged tissues and requires a combination of cells, growth factor and porous scaffolds. Scaffolds, as one of the main components in tissue engineering, are used as a template for tissue regeneration and induction and guidance of growth of the new and biologically active tissues. An ideal scaffold in tissue engineering, imitating...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutical Sciences
سال: 2015
ISSN: 0928-0987
DOI: 10.1016/j.ejps.2015.03.003